Sleep related breathing disturbances can be differentiated in various phenotypes, especially obstructive sleep apnoea, central sleep apnoea and hypoventilation disorders. Central breathing disturbances represent about 10% of the population of sleep apnoea patients. Several underlying diseases predispose to central sleep apnoea, with heart failure with reduced and preserved ejection fraction being the most prevalent comorbidities. Several studies have shown the impact of central sleep apnoea on mortality of heart failure patients. CPAP and oxygen may reduce central breathing disturbances by about 50% and data on long-term outcome are missing. Since its introduction into clinical practice, adaptive servo ventilation has been studied in several cohorts and randomized controlled trials. It normalizes central breathing disturbances, improves oxygen saturation and left ventricular ejection fraction. However, data on long-term outcome are controversial. Therefore, this program will discuss different algorithms of adaptive servo ventilation, the results of cohort studies and randomized controlled trials and discuss current options and future perspectives.
This activity is intended for medical professionals who have a clinical interest in the management of respiratory patients as seen by the following medical specialists: Pulmonologists, Pneumologists, Respirologists, Respiratory Physiotherapists, Respiratory Therapists (Hospital, Home), Thoracic Surgeons, Home Healthcare Providers, Critical Care Medicine Specialists, Internal Medicine Specialists, Primary Care Physicians (General and Family Practitioners), Advanced Practice Nurses, Nurse Practitioners, Physicians Assistants, Managed Care Medical Directors, and other Practitioners and Payers.
After completing this activity, the participant should be better able to:
- Describe the heterogeneity of phenotypes of central sleep apnoea.
- Discuss the pathophysiology of central sleep apnoea in heart failure.
- Explain the algorithm of adaptive servoventilation and its differences.
- Summarize the impact of central sleep apnoea on outcome of heart failure patients.
- Identify differences in outcomes of large randomized controlled trials and cohort studies.
Prof. Dr. med. Winfried J. Randerath
Professor of Medicine
Clinic of Pneumology and Allergology Center for Sleep Medicine and Respiratory Care
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This activity is provided by Global Education Group.
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This activity was released on November 16, 2023 and is valid for one year. Requests for credit must be made no later than November 15, 2024.
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Mozilla Firefox, Apple Safari, Google Chrome
For HTML Client – Google Chrome (v70.0 & above), Apple Safari (v12.0 & above), and Mozilla Firefox (v65.0 & above)
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Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.
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The faculty have the following relevant financial relationships with ineligible companies:
|Name of Faculty or Presenter
||Reported Financial Relationship
|Winfried J. Randerath, MD
Consulting Fee: Bioprojet Desitin
Contracted Research: Philips Respironics, Desitin, VitalAire, Onera B.V.
Honoraria: Jazz Pharmaceuticals, Bioprojet
Speakers' Bureau: Philips Respironics, Bioprojet, Jazz Pharmaceuticals, Proctor & Gamble, Habel Medizintechnik
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