Activity Title

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Adaptive Servoventilation in Central Sleep Apnoea:
Current Knowledge And Future Perspectives


Program Goals

Sleep related breathing disturbances can be differentiated in various phenotypes, especially obstructive sleep apnoea, central sleep apnoea and hypoventilation disorders. Central breathing disturbances represent about 10% of the population of sleep apnoea patients. Several underlying diseases predispose to central sleep apnoea, with heart failure with reduced and preserved ejection fraction being the most prevalent comorbidities. Several studies have shown the impact of central sleep apnoea on mortality of heart failure patients. CPAP and oxygen may reduce central breathing disturbances by about 50% and data on long-term outcome are missing. Since its introduction into clinical practice, adaptive servo ventilation has been studied in several cohorts and randomized controlled trials. It normalizes central breathing disturbances, improves oxygen saturation and left ventricular ejection fraction. However, data on long-term outcome are controversial. Therefore, this program will discuss different algorithms of adaptive servo ventilation, the results of cohort studies and randomized controlled trials and discuss current options and future perspectives.

Target Audience

This activity is intended for medical professionals who have a clinical interest in the management of respiratory patients as seen by the following medical specialists: Pulmonologists, Pneumologists, Respirologists, Respiratory Physiotherapists, Respiratory Therapists (Hospital, Home), Thoracic Surgeons, Home Healthcare Providers, Critical Care Medicine Specialists, Internal Medicine Specialists, Primary Care Physicians (General and Family Practitioners), Advanced Practice Nurses, Nurse Practitioners, Physicians Assistants, Managed Care Medical Directors, and other Practitioners and Payers.

Educational Objectives

After completing this activity, the participant should be better able to:

  1. Describe the heterogeneity of phenotypes of central sleep apnoea.
  2. Discuss the pathophysiology of central sleep apnoea in heart failure.
  3. Explain the algorithm of adaptive servoventilation and its differences.
  4. Summarize the impact of central sleep apnoea on outcome of heart failure patients.
  5. Identify differences in outcomes of large randomized controlled trials and cohort studies.


Prof. Dr. med. Winfried J. Randerath
Professor of Medicine
Clinic of Pneumology and Allergology Center for Sleep Medicine and Respiratory Care
Bethanien Hospital
Solingen, Germany

CME Provider Accreditation Statement

This activity is provided by Global Education Group.     

Physician Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the providership of Global Education Group (Global). Global is accredited by the ACCME to provide continuing medical education for physicians.

Physician Credit Designation

Global Education Group designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Education

Global Education Group is accredited with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.

This educational activity for 1.0 contact hour including 0.0 pharmacotherapeutic contact hours is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioner Continuing Education

AANP Logo  Global Education Group is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 110121. This activity is approved for 1.0 contact hour(s) (which includes 0.0 hour(s) of pharmacology).

Credit Designation - AARC

This Non-traditional program has been approved for 1.0 contact hour Continuing Respiratory Care  Education (CRCE) credit by the American Association for Respiratory Care; 9425 N. MacArthur Boulevard, Suite 100, Irving TX 75063

How to Obtain AARC / CRCE Credit

Attendees are expected to review all academic materials before attempting to apply for credit. Successful completion of this activity will lead to the issuance of a certificate for 1.0 contact hour of CRCE approved continuing education.

To receive credit, please follow these steps:

  • Complete the online registration (registration is free).
  • Review all of the academic materials provided.
  • Click on the CRCE link to apply for credit.
  • Complete the online test and/or evaluation. Participants must receive a test score of at least 70% and answer all evaluation questions to receive a certificate.
  • Qualified applicants will be provided with an online (printable) CRCE certificate based on their attendance and satisfactory completion of this academic activity.

Term Offering

This activity was released on November 16, 2023 and is valid for one year. Requests for credit must be made no later than November 15, 2024.

Global Contact Information

For information about the accreditation of this program, please contact Global at 303-395-1782 or

Instructions to Receive Credit

In order to receive credit, participants must complete all of the course lessons. Participants must also score at least a 70% on each chapter quiz. Upon completion of lessons and quizzes, you must also complete the evaluation form. Your certificate will be available to download upon completion of the evaluation.

System Requirements

PC 1.4 GHz Intel Pentium 4 or faster processor (or equivalent) Windows 11,10, 8.1 (32-bit/64-bit),            Windows 7 (32-bit/64-bit) 512 MB of RAM (1 GB recommended)

Microsoft Internet Explorer 11 or later, Windows Edge browser, Mozilla Firefox, and Google Chrome

For HTML Client – Google Chrome (v70.0 & above),          Mozilla Firefox (v65.0 & above), and Edge (v42.0 & above)

MAC 1.83 GHz Intel Core Duo or faster processor 512 MB of RAM (1 GB recommended) MAC OS X 10.12, 10.13 and 10.14

Mozilla Firefox, Apple Safari, Google Chrome

For HTML Client – Google Chrome (v70.0 & above), Apple Safari (v12.0 & above), and Mozilla Firefox (v65.0 & above)

Fee Information

There is no fee for this educational activity.

Disclosure of Relevant Financial Relationships

Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global.  All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias. 

All relevant financial relationships have been mitigated.

Faculty Disclosures

The faculty have the following relevant financial relationships with ineligible companies:

Name of Faculty or Presenter Reported Financial Relationship
Winfried J. Randerath, MD

Consulting Fee: Bioprojet Desitin

Contracted Research: Philips Respironics, Desitin, VitalAire, Onera B.V.

Honoraria: Jazz Pharmaceuticals, Bioprojet

Speakers' Bureau: Philips Respironics, Bioprojet, Jazz Pharmaceuticals, Proctor & Gamble, Habel Medizintechnik

The planners and managers at Global Education Group has no relevant financial relationships to disclose.

Disclosure of Unlabeled Use:

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) does not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.



Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Policy on Privacy and Confidentiality

Global Education Group (Global) protects the privacy of personal and other information regarding participants, educational partners, and joint sponsors. Global and our joint sponsors will not release personally identifiable information to a third party without the individual's consent, except such information as is required for reporting purposes to the appropriate accrediting agency.

Global Education Group and Dane Garvin, Ltd. maintain physical, electronic and procedural safeguards that comply with federal regulations to guard your nonpublic personal information.

Commercial Support Statement

This activity is supported by an educational grant from Philips Respironics, Inc.


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